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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f720fb1606e6922a20a306d6bd9a38effe021eab53bb4e86ed7808d7d6c30187' 
  AND token = 'Ily/NytbwuuXzPgXISdw9589Am6yNxCAxHV/Dr5sY0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}