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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc206f201c1aff750e054fab0f9f545f002f55ee67cebd051fc1b2007f13e2c0' 
  AND token = 'Y/4v+tvQFdHmm5ZX9BtEF6LIY+dlwfPiWlD6XYwkTvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}