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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a995de44e9594a1bbd2e02222150716af58156387df20cd34427a5779f5bbd' 
  AND token = 'CrR0xYmymf+DqKzHSsTjBijzx0CQ8imd4LNM/nR4y8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}