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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188fcc9f0dad9438c27f7989e56dae63d9c813c51738c1e6c53df5c442174d43' 
  AND token = 'xEQRqKun8KK/hfzYYrJARCoQyIVqEP7mJudJMCNXZi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}