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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b23aca3f8c2abfb9c406deae6dcecfda0acda41d224f7ff45fa0bc4bd6da738' 
  AND token = '1UT/Gvyma6wdZNlFp0PLSu51alSqcE9nnI9jDLcWchE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}