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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e8cc248833c8979a296b422f0755fad690e00e45e9cb90eb362fa743e4e944' 
  AND token = 'pzk3l8IUyH14oud5/QZmB40fijmcP/aK0F/mo8autHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}