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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e3579dabd7442f882e0553387581bdbab0e8046e598903a00333c835d270df' 
  AND token = 'gEf8qrrGT4cZZxnQURX5sQtKVIr/jqNut4kFy6jhoAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}