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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59814e080536f7e70658e46c8e6f8378a4bd6c6e43f7e44ece9796783ec4c0a' 
  AND token = 'c1jN61n9qAkIbvcH8J+XTcJLMDIoyfSByauajUzfSbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}