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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186f20ae1a2f460a51fcab9eff35fac728322ead6171003a9f2f028d56e57e1d' 
  AND token = '8n09C13mBfrcnFIW49yaWbfnCFebL+6BZdXPBboe2n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}