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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c9f1f48d043cace21da8435e31c73d4d96c3bf1b2317741178a0f97a227c42' 
  AND token = '63ZhzcNIjycHo/5MQCBrqjiN1znUtpqex120yGN4SUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}