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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e3c3577b99a0458d2d79a845cb45532ed05805764c0f910a179a2232e2f7f4' 
  AND token = 'ZZ1Y5hZOwBe0xPOhBDbxhWM9rrCrsTEM8MdBBguSCik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}