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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d18a1a8ace26e2f7a9bec90bcf1e6f76c8250ea3691aed740072ebdfc5e7b2d' 
  AND token = 'mdPUKyNsw5EaaEAvEeZOyO9NtvsVhcWgoJWiR54ioFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}