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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '673141f805440854546fa29529c9140d2506da3574041f481ef37ee5f7b7eaf3' 
  AND token = 'R3c9IP1+PS1LKvQxFQlrka5GpY8e69XnZbkMTZez5xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}