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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9744b0d65ced8ed6c9b3649109fe8476dacf17683287ccbef588593c5374f2e7' 
  AND token = 'pdNIHSxkKNtqDcLIxDG29fm9TV2Xq6XQTzw5rCpgH3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}