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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e886d849dc37334c9f5df717e31b4f07f745f378d41f4783949fe9dd81729c52' 
  AND token = 'QyQ5npYoOMJK3QZ1Kp55+Vaw3EXeDiRkm6ntMu4txWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}