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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f4de40a47de6aec44213bf8c2e20027a25994d4a549935dcf0cf090965f9554' 
  AND token = '809+gYcurHeMyerhzbcm6rSl29QKAjJdJwcRYHI/zwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}