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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f826919a719a27c21df85dc910c65d8c07c6c0812968fc2fc171eed302f0e4f' 
  AND token = '2o/etmAKtyhU45fFMv+3Gm7vQGbF6QaHYMxNkYaVhhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}