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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '547310aafe71f4b5b9f1158d6d85f5f4c1d41597801bc3c387024e9c75ea5646' 
  AND token = '03EQMQmNhCxDSS1equY7FMVXOtSaYAwIGc1W6sMg+UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}