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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddef8ca8519c1e8c52f2706a98f100ca4266bbdf23cc07974cf5aaa45ba921ce' 
  AND token = 'XPvhVStxId22R29WH0f+JEVs5V9dkZDjmE+yAGtYIZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}