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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4b7e630414ace9fd5ca14e51c38300524b9b502b70496217e2199ae6391e7c4' 
  AND token = 'h+SMUdyMK3vOwjRAah5T/aFNt4vd/ELPzd77Xg5KLtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}