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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6819cc3737b2b0acb51b76a6069ef387fc111ef53ae43983304d4e6436ceb6c' 
  AND token = 'N1Je9dc8g04TPoAsfQLM2cP7ALYNfIfiEr2UTLGf7A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}