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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4dcb951210ed359859b50c583b9c35afe75868e97e53ef94641d5d6f704725c' 
  AND token = 'myA6ym9+JZq7pyq/VvpDXzsN+wQ999G4bIW6+7XWyZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}