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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cfb8b09981fb583cf606224cd32a68fde1335f304732903dd0a97dfbec3bf3' 
  AND token = 'Vgo95tSeMArvrlYbF++sbLZk0CyCaSkpJ0qRArf+WNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}