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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654bb6f5cf89ea5126b37442381d987f47d0ba3ebfa1a2a36732e4636f4e154a' 
  AND token = 'MHHOBEFNSiiLcB1hmVTpyx8eFCAPkf014T2ITqQpE8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}