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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9189fb84e025a66b4bcbac5ba9312401e21db7a46c2fd854b4a698b3e04637e5' 
  AND token = 'F8zb+LUEDrCihnDtBKy18pjviEU+kYkd28jRzs93XhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}