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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43aacda30f44c88f2980d9ab8dd547d2a04ee5620f05c1af4c25c04d1f326aae' 
  AND token = 'USxdE3O9Cls0EfVVj5Yc4WDOpCbG9dPNc/puXKHzUD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}