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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f148302286c0f387d399d47b84a96443df5780afe0c9b7e3de048184a57f554' 
  AND token = '41AA7SpQqn3ONGlGAUDTGE7Xo8wO8rpxXLHIEMAXJyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}