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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2601b04e5ce0ca7fd271a463b0e8f839548e9e239a03709325cb4495c81fcca' 
  AND token = 'PH1BixzaekQK/h/+kz8AcoGsXj4bVbkEao5UZ6m9LlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}