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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801f123a7fa67273351403e627e238a8825b97a258f64b7671e756f5be5d2809' 
  AND token = '4zIwr9cu5aD5IFhAT1qQtxrC1L4unfuIoOP99C7gZZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}