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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891f3f448318ed61258e4c453470b0f99d03bcd83f6a51c6d07158e352b0207c' 
  AND token = 'D/SrSfo7FZ+acSrDl/aJ6PMaokUOIEaRH9g7RmfDJpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}