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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953808bda56d6d25b81978b07b1dce6d147bdf51098830b626e85bdcc3f74fc5' 
  AND token = 'A0BRn3C8+Zg6I4nUGNWAgziNafbIjQus9sTfsjV4YkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}