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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10787385c9765ca6f0158db6c495fe6cd14990c3eb46b86ee4bf81d5e4bee02e' 
  AND token = 'TCpfHgw3YkUaJvzcqkKn6d5eHaLV3nS2VR4HZ13VByg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}