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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fbc3c810201c0f50e83badacb3213c07521d1725f14e20cbc6bf522e4068fd' 
  AND token = 'mTHUSGzW4BLfTGWv1MuR5ElL+cZUdpRYIBUiNs/nGzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}