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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646808ac39ab67c73916d9b8d401df81614304596ce05f9663b0f335d7afbdcf' 
  AND token = 'Ud1dMgVTj07eIB/WXIitZBMb2NhxlGhO27yzip//z6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}