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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be93ff8c5abca8f1c314e98a411f7f109758aa33ab33ad239f68d0473dde42b' 
  AND token = '2upJZ0nQloR2ojBZB4h9u9Um2um4nuScUfnlby8rkKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}