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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395477f41980de8f4258ee90e9de3228b6fe987db7fd2c25a4c959d5f5f3682f' 
  AND token = '7Z0Lrg2JaJHmJ2s/Gue8CqJMk+7qG7l5It0XsKe0+zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}