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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e069e3c336c5d434f845ebe0bc13e2134c30d280d8310cdbc5053550cfa9f710' 
  AND token = '7QY/vCcJ9fAKii1aE0u2m3JiWXcNdUQT0OuE4TrCelg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}