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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2214766b424825dc568a460d5137e4eb1d9d8e7d61d7b0021e43c998657862b' 
  AND token = '6GWuLR42fpCyPhK0e6mrHDMkwG6pGWIDhOnoBxqUzGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}