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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd762b9ed9fd5ccc3336de081c33f0a2224d8c96aae2324d200be073027008749' 
  AND token = 'hE/DYw//TomNlB5aoIzoQYA7cKX8AcZ0wRMqvK8q9Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}