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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d87297cf76383f787e28744574ccb99726e40eaa26e05a1fa0e074d50f5de4a' 
  AND token = 'KTTJqIpnDeGaZpCPo78cQYGxMEM/gJBEwvU3bNA4NIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}