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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0446f3dd5f2ffb2e928768964bbdd4b8b17802fb5ec22ebd8727ac974ad944dd' 
  AND token = 'EirQMQF/aY06/3atUWFEqdAUcgEzWJgRYJ7KXeX4oNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}