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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1fd018d493e337a6b407f8bbd95c2cbbc65ce2a26600e22472f0c053e9f3a4' 
  AND token = 'F+K7cBBgeUstoP6x2i5yEAcwqTpXZJVjnyF2h26xGKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}