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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159af7063f459cdd2e26e79b1cc23d852de2a4ff340d44cddd2d7e1c0e3a0cf3' 
  AND token = 'Rw6lg+gUFTi/U1KXgZK7OklvbRtx6fPql4E5S349DNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}