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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3aeac49c3dcb76dfa2f3656c7c5dbf5133ceb56ecd7f382433c509dce97808' 
  AND token = 'pYDBhEqkfpJJEpg29rc1bRgEu+gYydb7yt30i2QqlaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}