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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7e0484af76e5a92586e09e4f537a471f901d74d8f9207ea600e3207b7f1249' 
  AND token = 'dS0lL7KNyis4qqUXwWQLn9bGbR1yZMpSWSj2cP8dWis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}