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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20bf1f111cc380f5e514d8819f0a1a53512439aeaf76e20040b379ad17637865' 
  AND token = 'vB1fV8ANJFTACcrsMOEo8Ak/8pxbpBhtXOHotxsg0xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}