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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b89f298ba34b3ea6f2c4c76c38a45ee188622db9c945c7fbb1333861b13f6182' 
  AND token = '3PjBy1z9injsIpYWtnETc5S1aG15/7yVL4ILHLMyRYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}