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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18cefb359fb12322c6af66f426332bf352799bea2cd67e7ef20ec5365378f446' 
  AND token = 'SyAvwCmBpyyzmv0vbKXz3vcK7zxO4j9lyADKfeK4xJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}