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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160031c8a3eb3555f791c62a7fa5f24e370229df2e23c79f5c52d353e0bbe071' 
  AND token = 'cD3tmAZP+y5L3YoxDdVTj0JvrGeZlyXY8S/jNqlLzd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}