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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d0350733178ea525f5c4b7a0a68286cd10ad1a34bc0a890f1695c72966edd0' 
  AND token = '9cDJrdeME6s285PxY981B+NZ3RCfutOV+40Nc5ceQKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}